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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ec33a4062c80ab268fa83dfe5b0bec16c5701da6d395d42b211c6215ed4840b' 
  AND token = 'wH9rJrHD5TQlP/V8N77OlWriwz5bC+32xWm+afJmkvo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}