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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '94f426e8a4042f46572af24f73a9bf059f702b7c7f751e656e7a4e1860ff9b24' 
  AND token = 'y2oqx33024S1TFw5XBWn5CuVxU4YvS2FuQ+lUC8GFa0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}