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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0053da8b1eb33483d5bc1e158a292bdc1ee257ae702b8ba74717fc3c69c26959' 
  AND token = 'bEOar4iBPcAhQumk/GLMpTcgAGGiAzHiTZo8j6WNfxs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}