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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7ddb0c742aafb6812170c13a787e611e32890bc8bb5d9ffb53127648623783c' 
  AND token = 'IzdqX+AE2zCObfxpp0c4WUmxtuN39/j0Zxu1Kv0JzE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}