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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12d976590d0147acca9ea8ea497ff0397b1cad413ef77e5115036f9ab60563a7' 
  AND token = 'KvkgOMayQ5Y10roUrnQl/K1XvFyE7zEY6n35ETxETCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}