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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de54ad428e7f460ea4ba9e82b16d562f30b6394b5e8444a6310180b91b0bd218' 
  AND token = 'Lj6ye15AvP2cxyiwhgYlJMLg6tLhKRxRP9KKMgpi3B8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}