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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae25b806e8c5c72727d076994fa513a325ef1180d9cd1d236a2d5bf395bf39e6' 
  AND token = 'sFtt+AzDOetMcPY76r8NIcmIZsZGx8cKZRXvZLKx8Og=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}