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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '428e52816ad5a6cc05713f2194039f50c8a1ee7ce06dfb810e94b49f28a1ce80' 
  AND token = 'L08HuOsqQ3/Pp7VSKAxJE0XTbhlZ+Hknkr6J6KQLmVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}