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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10c82dc4fab24f56e58ed1d11f7293d17bc05c9d6261ff814a7412474ad4fc73' 
  AND token = 'o5Rr7GOhCL1PuF5IT1lnB+pgKDxMLiBwT3Ycg4h16VQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}