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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc46d169c96a5c4d65d95e12363d393841482bb8ad2c2e13c2182a27b81cf35d' 
  AND token = 'OS/vZExRaSQNg7sgUdvnxn6d4b6PM6FSzYyQv42YsoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}