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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a49ae53b27375c92d8b0d1fac82a1f7962b6bb2c565938e9a1caf72c2800b67' 
  AND token = 'UXKBJSKmLcqVmN3z2yEsR+b7liJ8ekv+TYTCqpOkxOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}