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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b09b08b9c010f544eef2b43bba8a1ea1178448118e73edb446bc0b1e59f2bf0' 
  AND token = '2aL0JQddybGOztaltDkksz8zq03UaO7DWPWjWBjfz3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}