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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd915fc2bb3846738e6a0dfbbe6f43a33198cd93d8e8f338f8cd1545e96062536' 
  AND token = '3e+XvbNqG06xcNHtH9FqOoISKzL7Nsob6CpOatmmheE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}