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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d3225304e2c8a8c41d606696e6ae51cb8ff8a972d3b9fe5a551e8ca0c0c5bcb' 
  AND token = '9ED6hDkxbNLPHmmr3DeowzCQ389J0nMspaoU1nUnB98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}