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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8795356664b9c9fb2a4e36ce11679a18e0cdaabc4ce05774fadec0482e522a9' 
  AND token = 'v7tq3FlweM9maOCnRig2G81XUC4C5pmzCBnRJZ5VaC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}