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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c3bd8c450dbfe1108e005242f890af93bea6025620ceb97912add19c42b53e3' 
  AND token = 'BiSx7k0HMSd2TUnurSZk+UTBEt5xKfcY+SuyBQsqAOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}