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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff4573b336876623f66366062c87926e08a4a20bc1f3cb8f732b811e4eab1cb1' 
  AND token = '+XlCywBMNZRHNXZE0wYac+wN2oNGaFL+zP4Hs+DkCLo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}