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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fa4436863dfac952d94553e6c37c193c7feba7c96583917ef1026e9be5948e4' 
  AND token = 'Nq6D3V3R+46/FVwW4Q+3U6y/m8h+PVDjglD7GLN3RFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}