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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '370f9c3e3461176c5442005099d98ddf1f16732993a63534989f6ebaee0dea42' 
  AND token = 'EqCdq6kw4NtebTYq4NwU0atZTOZLcWKSCsZfCA5oFz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}