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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65e2c4ba1a7e024d32ea5a361d8425edc2e102bf76a42b9d8d8fae4d16bf2730' 
  AND token = 'aFoZ8opTXSXRI4c9A/favFJqdc27mqk+dnQA+VCo3BI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}