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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b504e181076cc24c6552cc5f88280cdbedaa7e7b1ef0d7c77e872c5aacbace5' 
  AND token = '1s38YbT3BVXmh0D/mbXLVQVThh3fxi3elFFA2HKLWuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}