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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fa5c18c0ce49c4489a5b75d251104a6e851ea18cc3539f1b4c8b8e06a2e7b1c' 
  AND token = 'L/qVF80mIusG8WOv1Ti7/O+3DWrYoOqZYk9IOdH2tl4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}