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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '047a2ad80ebd6a45b1c753c28f44b952889e180611e91cca6e3b66497c843919' 
  AND token = 'RmE8oDrmu3AqaO3n9VGUr9RPOzGswiKZHpPweLMN/gc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}