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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acadf89f3536fa8a97f7cbde017129526fc08518f1ddbe81e2468967dbbe6ad9' 
  AND token = 'yJFH3O7uPXwU4NH0Pbsse2JPW1PZRMSA5s5xm/PXeGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}