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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7ca7083017ee19f19fc1bbf1d9b330349aa27e56dd0c645d7d80ab68bd04f4a' 
  AND token = 'pIrtbRMXmvyJE9Vz/I/6OTzzc47P9UrKq2R6u4mzpxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}