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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3488dc820b7f258477fa1b8a4b90aebe138c371603a0a53bf8bb453ec2a655b1' 
  AND token = 'WnQUVMAsf6rEmNSadS9JzYENJVFToEn36ydro0U6tmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}