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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '816ce97247c58c8965f6d6a213ff043d9e351be2b71f8474500a5908d84e0664' 
  AND token = 'OXvRoghi0tHv31kKdQJMZ5boAbXlgZFD+9XS01bM1YE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}