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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e01ad807f746729c38916b10fc98fafd22ad46de66862f57273ec4371c949c6a' 
  AND token = 'vl8xuH+C+7Og5cJkoMsW7enV+nxOAof5cMhNzzHge1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}