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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4762117b82f35c7dff1b88b0ca757381078f7e9fcf0f1f23c68099a9feae30c6' 
  AND token = 'xhK+VVV5oUdQFXGa0WmxEpRArj6uE1IBaqtF39eRNAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}