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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e53c0a16e46db96ec05179448e16510151651478c44b6a58cc54293ba06ac29c' 
  AND token = '1fo1v/AtFoOR77VE2eSKnUPDIbZMSWICdQGTiCChC5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}