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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50d3157aa3a6aac45cc8b03fac364deb4f8aea6bc90b416251049032ca28a8e9' 
  AND token = 'daWeELg0rUtkGt3zRiv6svjdH62YudXjYn0XOPwMm0w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}