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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '188b7f78404490ad6fe26636d3e6468c2ee2369a1f2bccd9f7c0ba1c062d4838' 
  AND token = 'qYHUIi8CtUe4dlLtLCByBXjCuZtOfUwZHuXoGXFweAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00157

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}