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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c374565a4d9ff5b4ac20c44beb9131b3cb77839d54c6a19415a5415fda0596f1' 
  AND token = '5xz88f9JKmCJPVWvHfKFiSRkEoZ+8CA5tf4BB8BmWPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}