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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b2c969affc2322a9049c6cf03d51c2e321718fda5a29d84082c73c799618f15' 
  AND token = 'HBsdKnm1r10QZtzatVZzLFQ789cBxLf0Q+fPA/t0Ils=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}