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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4525f76db2472aedf3a34f6d650f0b4f8ecfddc5c2342b6c571b6f6a38fe34a0' 
  AND token = 'jtBi0ouh3TyPMb1qgOpzA+TOKMzFaHQMLugeVuCDlfI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}