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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '429d313898012b4d9c99efbb53852098ee554c19fee0a38c2e865fb030df1fe2' 
  AND token = '1WH6hzLiAS62wIZfYhiz5INawTbFysQAWuUBupWBXNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}