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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bd18708e7224fddfb5cf3d7e7f93f06e1d244c8a64953b81cdf1372dfff4d5b' 
  AND token = 'Xaos/52Waq0qy6wZdLcxiDJ8It24UZk3jEadTV1zbTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}