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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f14475c4f4e202d085deb36a735726fb382b41d44bf1e33d016618e726ebdc39' 
  AND token = 'yMESL25tOb0BXkGao9u0xzebg9snO+oyC023kdbxyGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}