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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cee8c332bdf9e3b04cf566d329429a9fd1c98b865bbf6eac0d72be578342d1f8' 
  AND token = '5Bg5DIHhAKMFOaD2FRamMMYxZs9OtrIBSamxij0JZ68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}