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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f49b7c59f5cfb3b24c35c93c6c0bf7a0591a516356788b0dce0b5c6428fbbd39' 
  AND token = '6dkUlIthx3exPXyqDY+MuQvs3ubhJzfyQrR9t9tNFH4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}