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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8a0be3f2a44bda2eed1180d819c75211b2c5622a87552f44390e141b798590c' 
  AND token = 'SlYl3+YJoYuyN3a5m8TnlIMzDCTU5rWdFLv2LrP84r4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}