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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1d164799ba33abaa3a44c721dfcc6b025c0f488ae3da37093f81be3aa415401' 
  AND token = 'tDGdcTdcxurkF5OazGK5kGoIRJG7YLcBQ5W5xSiChv4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}