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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3680f0c6eae488d1b9955c2c2ba03a0f7db233baec65c9aba13a51e4ee0d3644' 
  AND token = 'IEF3q1t0GfvArk6e7I68Hx+Pvuw2fqrBA3IkHOcXGTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}