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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df3a07e1f8ca5b11ab6773a3b34a0c27b91ab5633c80889c6014a124c4819c06' 
  AND token = 'aIsj2UcDdp5nNOLeCq/2GncGHEEA+GM+XnaeBZfmVug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}