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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3b80b4a8663f77420ffb81946b2850dc4dd187d58780a69d7438479ee731d3c' 
  AND token = 's/sZQ3R2dCHzOqoR7Fo2Hs11mrWlXlMXiuqbsvBt4RE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}