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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '379762770c091c162be889a9b2551d8dda4a618dfa1525d5b2a81f41f51baa62' 
  AND token = 's487fhmZcdFS8r4GZ5LirAo+KPTLhY8fLdng6CISJ3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}