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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6ec245e1d17b5846a2eb407e1d68cd300739d4a93715e11cbb8bb7a3e03830f' 
  AND token = 'tcwy6ZQeXUKGCFmHQVzrMMWC94oj9lpx4R3V/kp+T2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}