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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5deb1e7c30f62bc19ff305cf95991858fd14018f2c336fe3569b34e4dbb816d' 
  AND token = '3iTAcUr+4ATLuwHhNDi5Yw9YwBdsQ0yaTOXwaGQo3qo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}