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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26b275e30a70a3b16db0123a0e6712149251b3aefe57a2fbbc21e6ea62da2f32' 
  AND token = 'wPnV+hnZnXTpgPtDLdX44hmcGNo6az9/0iV0WisMGj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}