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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10182674dcce79acfb308e54af5ba37c92745283c304b1e3acd22786f3c42394' 
  AND token = '6jozHceS5Q7dsaLCOnaHef6pwyUBi4S5OPezTqhJIAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}